Chemical Name |
CAS Number |
RD50 (ppm) in different mice, |
References |
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mostly male: SW, B6C3F1, OF1, CF1 |
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BALB/c 57B1/6J and NIH/S |
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p-dichlorobenzene |
106-46-7 |
270 |
Dudek, B.R. et al. (1992). J. Toxicol. Environ. Health 37: 511-518 |
acetic acid |
64-19-7 |
227 |
Gagnaire, F. et al. (1993). Ann. Occup. Hyg. 46: 97-102 |
hydrogen peroxide |
7722-84-1 |
113 |
Gagnaire, F. et al. (1993). Ann. Occup. Hyg. 46: 97-102 |
peroxyacetic acid |
79-21-0 |
5.4 |
Gagnaire, F. et al. (1993). Ann. Occup. Hyg. 46: 97-102 |
chlorine |
7782-50-5 |
2.5 |
Gagnaire, F. et al. (1993). Ann. Occup. Hyg. 46: 97-102 |
nitrogen trichloride |
10025-85-1 |
3.5 |
Gagnaire, F. et al. (1993). Ann. Occup. Hyg. 46: 97-102 |
D-Δ3-carene |
|
1345 |
Kasanen, J-P. et al. (1999). J. Toxicol. Environ. Healt 57: 89-114 |
L-Δ3-carene |
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inactive |
Kasanen, J-P. et al. (1999). J. Toxicol. Environ. Healt 57: 89-114 |
turpentine |
8006-64-2 |
1173 |
Kasanen, J-P. et al. (1999). J. Toxicol. Environ. Healt 57: 89-114 |
D-α-pinene |
7785-70-8 |
1053 |
Kasanen, J-P. et al. (1998). Arch. Toxicol. 72: 514-523 |
L-α-pinene |
7785-26-4 |
inactive |
Kasanen, J-P. et al. (1998). Arch. Toxicol. 72: 514-523 |
(+)-α-pinene |
7785-70-8 |
2125 |
Nielsen,
G.D. et al. (2005) Basic & Clinical Parmacol. Toxicol. 96: 420-428 |
(-)α-pinene |
7785-26-4 |
rd50 could not be reached, but some activity |
Nielsen,
G.D. et al. (2005) Basic & Clinical Parmacol. Toxicol. 96: 420-428 |
D-β-pinene |
|
1279 |
Kasanen, J-P. et al. (1998). Arch. Toxicol. 72: 514-523 |
L-β-pinene |
|
4663 |
Kasanen, J-P. et al. (1998). Arch. Toxicol. 72: 514-523 |
1-octene-3-ol |
3391-86-4 |
35 |
Korpi, A. et al. (1999). Arch. Environ. Health 54: 347-351 |
3-octanol |
589-98-0 |
256 |
Korpi, A. et al. (1999). Arch. Environ. Health 54: 347-351 |
3-octanone |
106-68-3 |
3360 |
Korpi, A. et al. (1999). Arch. Environ. Health 54: 347-351 |
1,2,4-trimethylbenzene |
95-63-6 |
578 |
Korsak, Z. et al. (1997) Int. J. Occup. Med. Environ. Health 10: 303-311 |
1,3,5-trimethylbenzene |
108-67-8 |
519 |
Korsak, Z. et al. (1997) Int. J. Occup. Med. Environ. Health 10: 303-311 |
1,2,3-trimethylbenzene |
2551-13-7 |
541 |
Korsak, Z. et al. (1997) Int. J. Occup. Med. Environ. Health 10: 303-311 |
4-ethyltoluene |
622-96-8 |
887 |
Korsak, Z. et al. (1999) Int. J. Occup. Med. Environ. Health 12: 85-92 |
4-ethyltoluene |
622-96-8 |
857 |
Swiercz, R. et al. (2000) Int. J.
Occup. Med. Environ. Health 13:307-315 |
farbasol |
|
640 |
Korsak, Z. et al. (1999) Int. J. Occup. Med. Environ. Health 12: 85-92 |
1-methylnaphtalene |
90-12-0 |
21.5 |
Korsak, Z. et al (1998) Int. J. Occup. Med. Environ. Health 11: 335-342 |
2-methylnaphtalene |
91-57-6 |
11.5 |
Korsak, Z. et al (1998) Int. J. Occup. Med. Environ. Health 11: 335-342 |
1,2,4,5-tetramethylbenzene |
95-93-2 |
150 |
Korsak, Z. et al (1998) Int. J. Occup. Med. Environ. Health 11: 267-272 |
n-butyl alcohol |
71-36-3 |
3010 |
Korsak, Z. et al (1993) Polish J. Occup. Med. Environ. Health 6: 35-41 |
m-xylene |
108-38-3 |
1360 |
Korsak, Z. et al (1993) Polish J. Occup. Med. Environ. Health 6: 35-41 |
methacrolein |
78-85-3 |
10.4 |
Larsen, S.T. et al (2000) Toxicol. Letters 114: 197-202 |
R-[+]- limonene |
5989-27-5 |
1076 |
Larsen, S.T. et al (2000) Human
Experimental Toxicol. 19: 457-466 |
S-[-)-limonene |
5989-54-8 |
1467 |
Larsen, S.T. et al (2000) Human
Experimental Toxicol. 19: 457-466 |
chlorine |
7782-50-5 |
2.3 |
Morris, J.B. et al. (2005) Toxicol. Sci. 83: 380-387 |
trifluoroethanol |
75-89-8 |
23300 |
Nielsen, G.D. et al. (1996) Arch. Toxicol. 70: 319-328 |
hexafluoroisopropanol |
920-66-1 |
165 |
Nielsen, G.D. et al. (1996) Arch. Toxicol. 70: 319-328 |
methyl hexafluoroisopropyl
ether |
|
>160000 |
Nielsen, G.D. et al. (1996) Arch. Toxicol. 70: 319-328 |
cyanuric chloride |
108-77-0 |
0.78 |
Rydzynski, K. et al. (200) Int. J. Occup. Med. Environ. Health 7: 149-154 |
sulfur mustard |
505-60-2 |
4.22 |
Vijayaraghavan, R. (1997).Arch. Toxicol. 71: 157-164 |
glutaraldehyde |
111-30-8 |
13.9 |
Werley, M.S. (1995). Toxicol. Indust. Health 11: 489-501 |
glutaraldehyde |
111-30-8 |
2.6 |
Zissu, D. (1994). Toxicol. Letters 71: 53-62 |
methyl-2-cyanoacrylate |
137-05-30- |
1.4 |
Gagnaire, F. et al. (2003). Ann. Occup. Hyg. 47: 297-304 |
ethyl-2-cyanoacrylate |
7085-86-0 |
0.7 |
Gagnaire, F. et al. (2003). Ann. Occup. Hyg. 47: 297-304 |
isopropyl-2-cyanoacrylate |
10586-17-1 |
0.6 |
Gagnaire, F. et al. (2003). Ann. Occup. Hyg. 47: 297-304 |
2-methoxyethyl-2-cyanoacrylate |
27816-23-5 |
1 |
Gagnaire, F. et al. (2003). Ann. Occup. Hyg. 47: 297-304 |
methyl tertiary butyl ether |
1634-04-4 |
4614 |
Tepper, J.S. et al. (1994). Inhalation Tox. 6: 563-569 |
formaldehyde |
50-00-0 |
4 |
Nielsen, G.D. et al. (1999). Hum. Exp. Toxicol. 18: 400-409 |
2-chlorobenzylchloride |
611-19-8 |
7.4 |
Alarie, Y. (1998). Arch. Toxicol. 72:277-282 |
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Above were
compiled by Y. Alarie from copy of articles obtained |
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by M. Schaper. August 2006. |
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